Oxygen Delivery
Systems
Complete study notes on Low-flow & High-flow oxygen devices, FiO2 values, Venturi mask colour codes, cylinder colour codes, oxygen therapy complications and high-yield MCQs — ready for NORCET, AIIMS & State Nursing Exams.
Key Term – FiO₂ (Fraction of Inspired Oxygen)
FiO₂ = The fraction (proportion) of oxygen in the gas mixture being inhaled. Room air = FiO₂ 0.21 (21%). Pure oxygen = FiO₂ 1.0 (100%). Higher the flow rate → higher the FiO₂ delivered to the patient.
| Feature | Low-Flow System | High-Flow System |
|---|---|---|
| Definition | Provides O₂ at flow rates LESS than patient's inspiratory demand — room air is entrained (mixed in) | Provides O₂ at flow rates that MEET or EXCEED patient's total inspiratory flow demand — no room air entrainment |
| FiO₂ | Variable — depends on patient's breathing pattern (rate, depth, tidal volume) | Fixed, precise, predictable FiO₂ |
| Examples | Nasal cannula, Simple face mask, Partial rebreather, Non-rebreather | Venturi mask, High-flow nasal cannula (HFNC), Aerosol mask, T-piece |
| Best For | Stable patients with mild hypoxia and normal breathing pattern | Patients needing precise O₂ control (COPD), critically ill |
| FiO₂ Predictability | ❌ Unpredictable | ✅ Predictable & precise |
Nasal Cannula (NC)
| Flow Rate | 1–6 L/min |
| FiO₂ Range | 24% – 44% |
| FiO₂ Formula | FiO₂ = 20 + (4 × L/min) |
| Indication | Mild hypoxia, COPD, home O₂ |
| Prongs | 2 soft prongs sit in nostrils |
| Advantage | Patient can eat, talk, cough |
| Disadvantage | Mouth-breathing reduces FiO₂; nasal dryness |
Simple Face Mask (SFM)
| Flow Rate | 5–10 L/min |
| FiO₂ Range | 35% – 55% |
| Minimum Flow | 5 L/min (to flush CO₂) |
| Indication | Moderate hypoxia, short-term use |
| Exhalation ports | Small holes on side of mask |
| Advantage | Higher FiO₂ than nasal cannula |
| Disadvantage | Cannot eat; claustrophobic; FiO₂ variable |
Partial Rebreather Mask (PRM)
| Flow Rate | 6–10 L/min |
| FiO₂ Range | 60% – 70% |
| Reservoir Bag | Bag must stay ½–⅔ inflated |
| Valve | NO one-way valve between mask & bag |
| Rebreathing | First 1/3 expired air re-inhaled (less CO₂) |
| Indication | Moderate-severe hypoxia |
| Disadvantage | CO₂ rebreathing possible if flow too low |
Non-Rebreather Mask (NRM)
| Flow Rate | 10–15 L/min |
| FiO₂ Range | 80% – 95% |
| Valve | One-way valve between mask & bag |
| Exhalation valves | 1-way valves on exhalation ports |
| Rebreathing | NO exhaled air re-enters bag (valve prevents it) |
| Indication | Severe hypoxia, CO poisoning, trauma, code situations |
| Disadvantage | FiO₂ still not 100%; uncomfortable |
Venturi Mask (Air-Entrainment Mask)
| Principle | Bernoulli's principle / Jet mixing (Venturi effect) |
| FiO₂ Range | 24%, 28%, 31%, 35%, 40%, 60% |
| FiO₂ Control | Colour-coded adapters (diluters) |
| Best For | COPD patients (precise low FiO₂ needed) |
| Advantage | Most accurate, fixed FiO₂ regardless of breathing |
| Disadvantage | Noisy, uncomfortable, limits mobility |
High-Flow Nasal Cannula (HFNC)
| Flow Rate | Up to 60–70 L/min |
| FiO₂ Range | 21% – 100% |
| Humidification | Heated and humidified gas |
| Indication | Severe hypoxia, COVID-19, post-extubation, ARDS |
| Advantage | Comfortable, reduces work of breathing, provides PEEP |
| Disadvantage | Expensive, specialised equipment needed |
Aerosol Mask / Tracheostomy Mask
| Flow Rate | 10–15 L/min |
| FiO₂ Range | Variable (set by Venturi) |
| Humidification | Always humidified via nebulizer |
| Used With | Tracheostomy patients |
| T-piece | Used with endotracheal tube / tracheostomy tube |
| Advantage | Provides moisture and O₂ simultaneously |
CPAP / BiPAP (Non-Invasive)
| CPAP | Continuous Positive Airway Pressure — one pressure level |
| BiPAP | Two pressure levels: IPAP (inspiratory) + EPAP (expiratory) |
| FiO₂ | 21–100% (adjustable) |
| Indication (CPAP) | Sleep apnea, pulmonary edema, mild ARDS |
| Indication (BiPAP) | COPD exacerbation, hypercapnic respiratory failure |
| Contraindication | Apnea, facial trauma, inability to protect airway |
Mnemonic – Venturi Colour Order (Low → High FiO₂)
"Beautiful White Oranges Yield Real Goodness"
Flow rates: 2 – 4 – 6 – 8 – 10 – 15 L/min (increases by 2 till Red, then jumps to 15 for Green)
Oxygen (O₂)
Body: Black, Shoulder: White
International (ISO) standard
Oxygen – India (BIS)
Full Black cylinder
Indian Standard (BIS 7468)
Nitrous Oxide (N₂O)
Body: Blue, Shoulder: Blue
Used in anaesthesia
Carbon Dioxide (CO₂)
Body: Black, Shoulder: Grey
Used in laparoscopy
Entonox (50% O₂ + 50% N₂O)
Body: White & Blue quartered
Pain relief in labour
Medical Air
Body: White & Black quartered
Used in ventilators
Helium (He)
Body: Brown, Shoulder: Brown
Used with O₂ in airway obstruction
Heliox (He + O₂)
Body: Brown, Shoulder: White & Brown
Upper airway obstruction
Oxygen Cylinder Colour – Most Tested (India vs International)
👉 Remember: In India, oxygen cylinders are painted completely BLACK (BIS 7468 standard). International ISO standard = black body with white shoulder (collar).
| Complication | Description | Prevention / Management |
|---|---|---|
| Oxygen Toxicity | High FiO₂ (>60%) for prolonged time → lung damage, ARDS-like picture, absorption atelectasis | Use lowest effective FiO₂; monitor regularly |
| Hypercapnic Drive Suppression (COPD) | COPD patients rely on low O₂ as breathing drive. High O₂ → removes hypoxic drive → respiratory depression, CO₂ retention | Target SpO₂ 88–92% for COPD. Use Venturi mask for precise FiO₂ |
| Absorption Atelectasis | High O₂ replaces nitrogen in alveoli → alveoli collapse when O₂ absorbed rapidly | Use humidified O₂; avoid 100% O₂ unless necessary |
| Retinopathy of Prematurity (ROP) | High O₂ in premature neonates → retinal blood vessel damage → blindness | Strict SpO₂ targeting in preterm infants (90–95%) |
| Nasal Dryness / Mucosal Damage | Dry, unhumidified O₂ at high flow dries nasal mucosa | Use humidifier with O₂ at rates > 4 L/min |
| Fire Hazard | O₂ supports combustion — naked flame near O₂ = fire risk | No smoking, no open flame near O₂ cylinders |
| Infection | Contaminated humidifiers/nebulizers → respiratory infection | Change humidifier water every 24 hrs; sterile technique |
Verify the Order
Check physician's prescription — flow rate, device, target SpO₂, duration. Oxygen is a DRUG — requires prescription.
Assess the Patient
Check SpO₂, respiratory rate, ABG (if ordered), level of consciousness, skin colour (cyanosis?), and signs of respiratory distress before starting O₂.
Select Correct Device
Choose appropriate device based on required FiO₂, patient condition, and ability to tolerate mask/cannula. COPD → Venturi. Emergency → NRM.
Set Flow Rate Correctly
Attach to O₂ source, set prescribed flow rate, confirm adequate gas flow before applying to patient.
Apply Device Correctly
Ensure proper fit (no leaks). Adjust mask straps. Position nasal cannula prongs curved downward into nostrils. Secure tubing comfortably.
Humidification
Add humidifier if flow rate >4 L/min or for prolonged therapy. Prevents mucosal dryness. Change humidifier water every 24 hours.
Monitor Continuously
Check SpO₂ every 15–30 min initially, then hourly. Watch for signs of O₂ toxicity, CO₂ retention in COPD, skin breakdown under mask straps.
Safety Measures
NO smoking within 3 metres of O₂. No petroleum-based products (Vaseline) near O₂ face — fire risk. Post "No Smoking / Oxygen in Use" sign.
Skin Care
Check behind ears and around face for pressure sores from mask/cannula straps. Apply padding as needed. Reposition mask periodically.
Documentation
Record: flow rate, device used, SpO₂ before & after, time started, patient response, ABG values, any complications observed.
| Device | Type | Flow Rate | FiO₂ | Key Feature |
|---|---|---|---|---|
| Nasal Cannula | Low-flow | 1–6 L/min | 24–44% | Most comfortable; can eat/talk; FiO₂ = 20+(4×L) |
| Simple Face Mask | Low-flow | 5–10 L/min | 35–55% | Min 5L/min; side ports allow CO₂ escape |
| Partial Rebreather | Low-flow | 6–10 L/min | 60–70% | NO valve; 1st 1/3 exhaled air re-inhaled |
| Non-Rebreather | Low-flow | 10–15 L/min | 80–95% | ONE-WAY valve; no exhaled air re-enters bag |
| Venturi Mask | High-flow | 2–15 L/min | 24–60% | Colour-coded adapters; most precise FiO₂; COPD choice |
| HFNC | High-flow | Up to 60 L/min | 21–100% | Heated + humidified; provides mild PEEP effect |
| CPAP | High-flow | Variable | 21–100% | One pressure level; sleep apnea, pulmonary oedema |
| BiPAP | High-flow | Variable | 21–100% | Two pressures (IPAP+EPAP); COPD exacerbation |
Nasal Cannula FiO₂ Calculation – Easy Formula
FiO₂ (%) = 20 + (4 × Flow Rate in L/min)
- A) 16%
- B) 18%
- C) 21%
- D) 24%
- A) 28%
- B) 32%
- C) 36%
- D) 40%
- A) 24% at 2 L/min
- B) 28% at 4 L/min
- C) 31% at 6 L/min
- D) 35% at 8 L/min
- A) Non-rebreather mask
- B) Nasal cannula
- C) Venturi mask
- D) Simple face mask
- A) 35%
- B) 44%
- C) 55%
- D) 70%
- A) Size of the reservoir bag
- B) Flow rate used
- C) Presence of a one-way valve between mask and reservoir bag
- D) Color of the mask
- A) 95–100%
- B) 94–98%
- C) 88–92%
- D) 80–85%
- A) Green
- B) Blue
- C) Black
- D) White with black shoulder
- A) Compression of gas under high pressure
- B) High-velocity jet of O₂ that entrains (draws in) room air to give fixed FiO₂
- C) Absorption of CO₂ by soda lime
- D) Positive pressure ventilation
- A) Oxygen toxicity
- B) Absorption atelectasis
- C) Hypercapnia
- D) Retinopathy of Prematurity (ROP)
- A) To maintain adequate FiO₂
- B) To flush carbon dioxide (CO₂) out of the mask
- C) To prevent the reservoir bag from collapsing
- D) To activate the Venturi mechanism
- A) 35%
- B) 40%
- C) 50%
- D) 60%
- A) Nasal cannula at 6 L/min
- B) Simple face mask at 10 L/min
- C) Partial rebreather mask
- D) Non-rebreather mask
- A) Change the mask to nasal cannula
- B) Remove the one-way valve
- C) Increase the oxygen flow rate
- D) Ask the patient to breathe slower
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